ETRIS: Education & Training Resources in In-Vivo Sciences

Experimental and statistical design

ARRIVE guidelines

The ARRIVE guidelines provide guidance on best practice in the reporting (including publication) of research which used laboratory animals.

The Animal Research: Reporting In Vivo Experiments (ARRIVE) guidelines and checklist comprise of 20 points to be covered when reporting studies involving laboratory animals including recomendations for the content of the title, abstract, introduction, methods, results and discussion sections of any publications. A modified version has been developed by the British Journal of Pharmacology

The ARRIVE guidelines were developed by the UK National Centre for the 3Rs. They have been adopted by over 100 major journals. Copyright is retained by the NC3Rs

This resource will be of benefit to those who use laboratory animals, design or publish studies involving laboratory animals, or those involved in the education and training of researchers. It could also be used as a checklist during the actual design of research studies.

Undergraduate and Taught Masters Research Animal Sciences curricula

This resource could be used in the delivery of the following Learning Outcomes:

  • Appropriate reporting standards for sharing of research
  • The concept that research animal welfare impacts upon reproducibility and reliability of data

Students could be provided with a copy of these guidelines and a published scientific paper, and asked to determine how many of these points had been included in the paper. This could then lead onto a discussion of what additional information would need to be provided, particularly with regard to animal welfare etc, to enable the studies to be reproduced. Alternatively, they could be used just to illustrate these Learning Outcomes in a teaching session.

Other resources in this category:

  • 3Rs-Reduction - view
  • ARRIVE guidelines - view
  • Assay Capability Tool - view
  • EMPReSS - view
  • Experimental Design Assistant - view
  • InVivoStat - view
  • Reproducibility and reliability of biomedical research - view
  • Reproducibility in Research - view
  • Systematic Reviews of Animal Studies - view

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