ETRIS: Education & Training Resources in In-Vivo Sciences

Educational resources and protocols

Anxiety responses in rodents

A Laboratory Exercise for a College-Level, Introductory Neuroscience Course Demonstrating Effects of Housing Environment on Anxiety and Psychostimulant Sensitivity is a journal article describing a laboratory session in which students investigate the effects of environmental enrichment or amphetamines on anxiety-like behaviours in rodents.

This article describes husbandry and care of the rodents, the experimental equipment and resources required, student protocols and data analysis. Students gain experience of experimental design, animal handling, use of different behavioural arenas, data capture (using ethograms), analysis and interpretation.

To ensure compliance with good practice in the 3Rs, it is recommended that the animal husbandry procedures described in the article be modified so that all animals are housed in solid-bottom cages with bedding material and singularly housed animals also have additional nesting material (as a minimum).

It was developed by Dr Pritchard and colleagues, Williams College, MA, USA and is published in the Journal of Undergraduate Neuroscience Education (Pritchard et al. (2008) JUNE (2008) 7 (1): A26-A32). Copyright is retained by the journal.

This laboratory session can be used in undergraduate student education as part of a larger in-vivo neurobiology course.

Other resources in this category:

  • Anxiety responses in rodents - view
  • Escape responses in Zebrafish - view
  • Glucose Tolerance Tests - view
  • In-vivo time-lapse imaging in the Zebrafish lateral line - view
  • In-vivo Voltammetry - view
  • Inexpensive Tail Flick Analgesia Meter - view
  • Microdialysis - view
  • Psychostimulant actions on rodent behaviours - view
  • Renal response to volume expansion - view
  • Sensory physiology - view
  • The zebrafish brain in research and teaching - view
  • Zebrafish in the Classroom - view

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